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Indications for facial transplantation continues to evolves as experience grows within the scientific community. In general, patients are considered candidates when the severe facial defect and functional deficits cannot be helped with conventional reconstructive techniques. Contraindications, likewise, vary from institution to institution, but general agreement lies with feasibility of adequate follow up, lack of financial support and/or history of poor medical compliance. Psychological issues compromising the patients ability to understand and cope with face transplant and/or comply with medical orders are absolute contraindications as well.

Table 1. Inclusion and exclusion criteria for face transplantation at Brigham and Women's Hospital

Wo, L., Bueno, E. & Pomahac, B. Facial transplantation: worth the risks? A look at evolution of indications over the last decade. Curr Opin Organ Transplant 20, 615-620 (2015).